The 1953 experiment of Miller and Urey was a watershed in "origin of life" research. It showed that under conditions that simulated the early Earth, amino acids and other biologically relevant molecules could be synthesized from inorganic starting materials in the laboratory.


    Animation of the spark-discharge experiment. The device shown was initially filled with ammonia, methane, and dihydrogen gases at pressures of 100, 200, and 200 torr respectively. These gases simulated the atmosphere that was assumed to exist on the early Earth. The flask on the lower left contained water that was heated to boiling. Since the lower flask contains water, the apparatus also contained water vapor. In the large glass bulb in the upper right, a spark discharge continuously supplied energy. Below the glass bulb was a condensing column that re-circulated materials from the large bulb into the liquid water.



    The video shows an actual re-creation of the Miller-Urey experiment. The apparatus is set-up as described in the previous animation. The original experiment was run for about one week, here we will view two separate experiments in time lapse. Be sure to observe carefully and note any changes that you see during the course of these experiments. On analysis of the reaction mixture, there were 19 organic compounds identified, including the amino acids: glycine and alanine.


    Spark Discharge | Origins of Life | ChemConnections